https://yourbrainonporn.com/garys-research-neuroplasticity-addiction-loss-of-plasticity "By comparing addict and non-addict animals at various time points during their history of drug taking, the teams of Pier Vincenzo Piazza and Olivier Manzoni have demonstrated that the animals which developed an addiction to cocaine exhibit a permanent loss of the capacity to produce a form of plasticity known as long term depression (or LTD). LTD refers to the ability of the synapses (the region of communication between neurons) to reduce their activity under the effect of certain stimulations. It plays a major role in the ability to develop new memory traces and, consequently, to demonstrate flexible behaviour." I know the above is an old article, but does the above quote say that if you've experienced addiction, your brain's plasticity is damaged.... probably forever??? If so, what hope is there for people like us??